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rhegfr  (Merck & Co)

 
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    Merck & Co rhegfr
    Rhegfr, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rhegfr/rhegfr/pmc11730255-171-10-13
    Average 90 stars, based on 1 article reviews
    rhegfr - by Bioz Stars, 2026-09
    90/100 stars

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    Produced:

    Article Title: Enhancing NK cell-mediated tumor killing of B7-H6 + cells with bispecific antibodies targeting allosteric sites of NKp30
    Article Snippet: .. Afterward, a first association step was performed using 100 nM rhEGFR (produced by Merck Healthcare KGaA), or alternatively, 100 nM rhHER2 (Sino Biological) for 3 min, followed by a second association with 100 nM rhNKp30 for 3 min. ..



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    Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in <t>an</t> <t>ELISA</t> assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to <t>rhEGFR.</t> y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.
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    Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in an ELISA assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to rhEGFR. y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: Peptide Vaccines and Peptidomimetics of EGFR (HER-1) Ligand Binding Domain Inhibit Cancer Cell Growth In Vitro and In Vivo

    doi: 10.4049/jimmunol.1300231

    Figure Lengend Snippet: Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in an ELISA assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to rhEGFR. y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.

    Article Snippet: ELISA was performed to evaluate the binding of the vaccine Abs to rhEGFR (R&D Systems) (as described in Ref. 20 ).

    Techniques: Enzyme-linked Immunosorbent Assay, Construct, Binding Assay, MTT Cell Proliferation, Inhibition